Histopathology is performed by a lab-based pathologist who, with the assistance of a medical technologist, prepares the tissues by sectioning them and placing them on a glass slide. The sample can then be exposed to dyes and other techniques to highlight, segregate, or remove cells so they are better viewed under the microscope.
Along with a biopsy (the extraction of tissues for lab evaluation), histopathology remains the gold standard for diagnosing many solid-tumor cancers. Histopathology can differentiate benign tumors from cancerous ones and is also central to cancer staging (determining how advanced a cancer is) and cancer grading (determining how aggressive a cancer is).